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  6. Dematin Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Dematin Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Product Code. 16836554 Shop All Proteintech Products
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20 μL
150 μL
Unit Size:
150µL
20µL
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16836554 20 μL 20µL
16826554 150 μL 150µL
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Product Code. 16836554 Supplier Proteintech Supplier No. 168081AP20UL

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Description

Rabbit Polyclonal Antibody

The protein encoded by this gene is an actin binding and bundling protein that plays a structural role in erythrocytes, by stabilizing and attaching the spectrin/actin cytoskeleton to the erythrocyte membrane in a phosphorylation-dependent manner. This protein contains a core domain in the N-terminus, and a headpiece domain in the C-terminus that binds F-actin. When purified from erythrocytes, this protein exists as a trimer composed of two 48 kDa polypeptides and a 52 kDa polypeptide. The different subunits arise from alternative splicing in the 3′ coding region, where the headpiece domain is located. Disruption of this gene has been correlated with the autosomal domit Marie Unna hereditary hypotrichosis disease, while loss of heterozygosity of this gene is thought to play a role in prostate cancer progression. Alternative splicing results in multiple transcript variants encoding different isoforms.

Specifications

Antigen Dematin
Applications Western Blot
Classification Polyclonal
Concentration 0.13 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene DMTN
Gene Accession No. Q08495, Q9WV69
Gene Alias Dematin, DMT, DMTN, EPB49
Gene Symbols Dmtn
Host Species Rabbit
Immunogen Dematin Fusion Protein Ag10300
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13829, 2039, 361069
Target Species Rat, Mouse, Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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