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Tocris Bioscience™ dBRD9-A
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Product Code. 18085112
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5 mg
Unit Size:
5mg
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18085112 5 mg 5mg
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Product Code. 18085112 Supplier Tocris Bioscience™ Supplier No. 6943/5

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Description

Potent BRD9 Degrader (PROTAC™)

dBRD9-A is a potent BRD9 Degrader (PROTAC™). Selectively binds BRD9 and elicits near complete degradation of BRD9 at nanomolar concentrations. Inhibits growth of synovial sarcoma cells in vitro and tumor progression in a synovial sarcoma xenograft mouse model. PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material 2-((2,6-Dimethoxy-4-(2-methyl-1-oxo-1,2-dihydro-2,7-naphthyridin-4-yl)benzyl)(methyl)amino)-N-(8-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)octyl)acetamide
CAS 2170679-42-0
Quantity 5 mg
Target Active Degraders
Molecular Formula C42H49N7O8
Purity 0.98
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