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Invitrogen™ DAXX Monoclonal Antibody (7A11)
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Product Code. 11385513
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Quantity:
100 μL
Unit Size:
100µL
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Product Code. Quantity unitSize
11385513 100 μL 100µL
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Product Code. 11385513 Supplier Invitrogen™ Supplier No. MA515552

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Description

Mouse Monoclonal Antibody

MA5-15552 targets DAXX in indirect ELISA, FACS, IF, and WB applications and shows reactivity with Human samples. The MA5-15552 immunogen is purified recombinant fragment of human DAXX expressed in E. Coli. MA5-15552 detects DAXX which has a predicted molecular weight of approximately 81kDa.

This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants.
TRUSTED_SUSTAINABILITY

Specifications

Antigen DAXX
Applications ELISA, Flow Cytometry, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 7A11
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation ascites with 0.03% sodium azide
Gene DAXX
Gene Accession No. Q9UER7
Gene Alias BING2; CENP-C binding protein; DADB-159G18.9; DAP6; Daxx; death domain associated protein; Death domain-associated protein 6; death-associated protein 6; death-domain associated protein; EAP1; ETS1-associated protein 1; Fas death domain-associated protein; Fas-binding protein; hDaxx; MGC126245; MGC126246; SMIM40; Unknown (protein for MGC:138055)
Gene Symbols DAXX
Host Species Mouse
Immunogen Purified recombinant fragment of human DAXX expressed in E. Coli.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1616
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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