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Dacomitinib, MedChemExpress

Product Code. 16496146
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Product Code. Quantity unitSize
16496146 100 mg 100mg
16485608 10 mg 10mg
16471777 50 mg 50mg
16438307 5 mg 5mg
16421076 200 mg 200mg
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Product Code. 16496146

Brand: Medchem Express HY13272

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Description

MedChemExpress Dacomitinib (PF-00299804) is a specific and irreversible inhibitor of the ERBB family of kinases with IC50s of 6 nM, 45.7 nM and 73.7 nM for EGFR, ERBB2, and ERBB4, respectively.

Dacomitinib (PF-00299804) is a specific and irreversible inhibitor of the ERBB family of kinases with IC50s of 6 nM, 45.7 nM and 73.7 nM for EGFR, ERBB2, and ERBB4, respectively.

Specifications

Chemical Name or Material Dacomitinib
CAS 1110813-31-4
Color Light Yellow
Purity Grade Notes Research
Molecular Formula C24H25ClFN5O2
Quantity 100 mg
Synonym PF-00299804 PF-299804
Solubility Information DMSO : 40 mg/mL (85.12 mM; Need ultrasonic)
SMILES O=C(/C=C/CN1CCCCC1)NC2=CC3=C(C=C2OC)N=CN=C3NC4=CC=C(C(Cl)=C4)F
Molecular Weight (g/mol) 469.94
Formula Weight 469.94
Percent Purity 95.0%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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