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  6. CYR61/CCN1 Rabbit anti-Human, Polyclonal, Proteintech

CYR61/CCN1 Rabbit anti-Human, Polyclonal, Proteintech

Product Code. 16855085 Shop All Proteintech Products
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150 μL
20 μL
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150µL
20µL
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16855085 150 μL 150µL
16865085 20 μL 20µL
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Product Code. 16855085 Supplier Proteintech Supplier No. 266891AP150UL

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Description

Rabbit Polyclonal Antibody

CYR61 is a secreted heparin binding protein, encoded by a growth factor inducible immediate-early gene that associates with the extracellular matrix and connective tissue. CYR61 is a member of a distinct family of angiogenic and vasculogenic regulators designated CCN proteins, which includes connective tissue growth factor (CTGF) and the mouse CYR61 homolog, Fisp12. As an angiogenic inducer, CYR61 binds to the cell surface receptor integrin alphavbeta3, where it then stimulates cell adhesion and migration and promotes DNA synthesis of human vascular endothelial cells. Expression of CYR61 is elevated during vessel growth, wound healing and chondrocyte differentiation. CYR61 is also detected in a wide variety of tumors as it induces tumor growth and functions as a marker of tumor progression.

Specifications

Antigen CYR61/CCN1
Applications Immunocytochemistry, Immunofluorescence, Western Blot
Classification Polyclonal
Concentration 0.33 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene CYR61
Gene Accession No. O00622
Gene Alias CCN family member 1, CCN1, CYR61, GIG1, IBP 10, IGF binding protein 10, IGFBP 10, IGFBP10, Protein CYR61, Protein GIG1
Gene Symbols CYR61
Host Species Rabbit
Immunogen CYR61/CCN1 Fusion Protein Ag25129
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3491
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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