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Invitrogen™ CXCR1 Chimeric Recombinant Rabbit Monoclonal Antibody (SE2)
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Product Code. 17921131
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Quantity:
200 μg
Unit Size:
200µg
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17921131 200 μg 200µg
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Product Code. 17921131 Supplier Invitrogen™ Supplier No. MA548299

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Description

Rabbit Recombinant Monoclonal Antibody

Specificity: SE2 antibody is specific for IL-8RA and does not corss-react with IL-8RB. IL-8RA is a receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils.

CXCR1 is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CXCR1 Chimeric
Applications Flow Cytometry, Immunohistochemistry, Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone SE2
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% ProClin 300
Gene CXCR1
Gene Accession No. P25024
Gene Alias C Cmotif chemokine; C X C motif chemokine; C-C; CC motif chemokine; C-C-CKR-1; CCmotif chemokine; CD128; CD181; CDw128a; chemokine (C-X-C motif) receptor 1; CKR-1; CMKAR1; CXC; CXC chemokine receptor 1; C-X-C chemokine receptor type 1; CXC motif chemokine; C-X-C motif chemokine receptor 1; CXCR1; CXC-R1; CXCR-1; High affinity interleukin-8 receptor A; IL-8 receptor; IL-8 Receptor alpha; IL-8 Receptor IL-RA; IL-8 receptor type 1; IL-8R A; IL8R1; Il8ra; IL8RBA; IL-RA; interleukin 8 receptor; interleukin 8 receptor alpha; interleukin 8 receptor, alpha; interleukin-8 receptor type 1; interleukin-8 receptor type A
Gene Symbols CXCR1
Host Species Rabbit
Immunogen This antibody was raised by immunizing BALB/c mice with a BSA-conjugated peptide comprising of the N-terminal part of IL-8RA (amino acids 1-30).
Purification Method Protein A
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3577
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG κ
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