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Ambion™ Custom Silencer™ siRNA
Description
Specifications
Specifications
| Content And Storage | Store at or below -20°C. Do not store in a frost-free freezer. (Dried oligonucleotides are shipped at ambient temperature.) Additional Materials Included: 1.75 mL Nuclease-free Water |
| Description | Custom siRNA, 20nmol, Liquid, Standard Purity, Water Soluble, RNAi is the best Way to Effectively Knock Down Gene Expression to Study Protein Function in a Wide Range of Cell Types, Use our GeneAssist Custom siRNA Builder to Design and Order a Custom siRNA |
| RNAi Type | siRNA |
| Sample Type | RNA |
| Product Line | Ambion™, Silencer™ Select |
| Product Type | Custom siRNA |
| Purity | Standard |
| Quantity | 20 nmol |
| Form | Liquid |
Frequently Asked Questions (FAQs)
For any RNAi duplex (miRNA or siRNA) there is a possibility that adding a modification will affect how the antisense strand interacts with RISC and aligns with its mRNA target, thus impacting functionality. For that reason, we recommend that you label the 5' end of the sense strand for siRNA (or passenger strand for miRNA). Since the 5' end of the antisense (guide strand) is what gets recognized by RISC, it is best to add the fluorescent modification to the end of the duplex on the strand that does not interact with RISC. You can also test a labeled vs. non-labeled RNAi duplex to determine if the modification is affecting the siRNA or miRNA functionality.
For Research Use Only. Not for use in diagnostic procedures.
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