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Tocris Bioscience™ CST 626
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Product Code. 30000663
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Quantity:
2 mg
Unit Size:
2mg
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Product Code. 30000663 Supplier Tocris Bioscience™ Supplier No. 8021/2

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Description

Potent pan IAP Degrader (PROTAC™)

CST 626 is a potent IAP Degrader (PROTAC™) (DC50 values at 16 hours are 0.7 nM, 2.4 nM and 6.2 nM at XIAP, cIAP1 and cIAP2 respectively; Dmax = 90-99%). Reduces cell viability in some cell types, including SUDHL6 and MOLM13 (IC50 values are 16 nM and 21 nM respectively).

PROTAC™ is a registered trademark of Arvinas Operations, Inc., and is used under license.

TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material (2S,4S)-1-((S)-2-Cyclohexyl-2-((S)-2-(methylamino)propanamido)acetyl)-4-(3-((5-(((S)-1-((2S,4R)-4-hydroxy-2-(((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-5-oxopentyl)oxy)phenoxy)-N-((R)-1,2,3,
Quantity 2 mg
Target Active Degraders
Molecular Formula C61H82N8O9S
Purity 0.98
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