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Tocris Bioscience™ CP 100356 hydrochloride
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Product Code. 18045342
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 18045342

Brand: Tocris Bioscience™ 4193/10

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This item is not returnable. View return policy

Description

P-gp inhibitor

High affinity P-glycoprotein (P-gp) inhibitor (Ki values are 58 and 94 nM for mouse Pgp1a and Pgp1b isoforms). Inhibits calcein-AM uptake in MDR1-transfected MDCKII cells (IC50 = 0.5 μM) and prazosin transport in BCRP-transfected MDCKII cells (IC50 = 1.5 μM). Displays weak or no inhibitory activity against MRP1, OATP1B1 and several major human P450 enzymes (IC50 > 50 μM).
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 142715-48-8
Molecular Formula C31H37ClN4O6

Specifications

Quantity 10 mg
Formula Weight 597.1
Purity >98%
Molecular Weight (g/mol) 597.109
Chemical Name or Material CP 100356 hydrochloride
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