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  6. Proteintech CoraLite™488 TUNEL Assay Apoptosis Detection Kit (green)

Proteintech CoraLite™488 TUNEL Assay Apoptosis Detection Kit (green)

Product Code. p-7224555 Shop All Proteintech Products
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50 Tests
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50 tests
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17531176 20 Tests 20 tests
17541176 50 Tests 50 tests
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Product Code. 17531176 Supplier Proteintech Supplier No. PF0000620T

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Description

A distinctive feature of apoptosis is degradation of DNA.

  • The DNA fragments tend to be vary in length in integer multiples of 180 bp-200 bp, which is shown as a ladder-like pattern in agarose gel electrophoresis.
  • This kit uses the TUNEL method, using Terminal Deoxynucleotidyl Transferase (TdT) to catalyze the incorporation of CL488-dUTP at the 3'-OH end of the broken DNA of apoptotic cells.
  • CL488-dUTP-labeled DNA can be directly observed with a fluorescence microscope or quantified with a flow cytometer.
  • The TUNEL method can selectively detect apoptotic cells, but not necrotic cells or cells with DNA strand breaks caused by irradiation and drug treatment.

Specifications

Description Emission: 515 nm
Quantity 20 Tests
For Use With (Application) Flow Cytometry
Storage Requirements Store at -20°C. Avoid exposure to light. Stable for 2 years after shipment. Avoid freeze- thaw cycles.
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