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Invitrogen™ COCH Polyclonal Antibody
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Product Code. 16550432
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Quantity:
100 μL
Unit Size:
100µL
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16550432 100 μL 100µL
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Product Code. 16550432 Supplier Invitrogen™ Supplier No. PA597602

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Description

Rabbit Polyclonal Antibody

COCH Polyclonal Antibody for Western Blot, ELISA

Cochlin is a secreted protein encoded by the coagulation factor C homology (COCH) gene, a cochlear gene. It constitutes 70% of the inner ear proteins and is classified into three glycosylated isoforms: p63s, p44s and p40. Cochlin contains an N-terminal LCCL domain and two von Willebrand factor A-like domains. Mutations in the COCH gene cause DFNA9, an autosomal dominant nonsyndromic auditory and vestibular dysfunction disorder, as a result of either an amino acid deletion in the LCCL domain or missense substitutions. Microfibrillar deposits accumulate in the inner ear of individuals with DFNA9 and these deposits may contain the Cochlin protein. Cochlin is a target antigen for autoimmune sensorineural hearing loss.
TRUSTED_SUSTAINABILITY

Specifications

Antigen COCH
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene COCH
Gene Accession No. O43405
Gene Alias AW122937; coagulation factor C homolog (Limulus polyphemus); coagulation factor C homolog, cochlin (Limulus polyphemus); Coch; COCH5B2; COCH-5B2; Cochlin; D12H14S564E; DFNA9; PRO294; UNQ257; UNQ257/PRO294
Gene Symbols COCH
Host Species Rabbit
Immunogen Recombinant Human Cochlin protein (20-260AA).
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1690
Target Species Human
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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