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Invitrogen™ CLN6 Polyclonal Antibody
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Product Code. 16683075 Shop All Thermo Scientific Products
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Quantity:
100 μL
Unit Size:
100µL
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16683075 100 μL 100µL
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Product Code. 16683075 Supplier Invitrogen™ Supplier No. PA5106641

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total CLN6.

CLN6, a 311-amino acid protein, has 7 predicted transmembrane domains and is conserved across vertebrates. The CLN6 protein localizes to the endoplasmic reticulum but contributes to lysosomal function. Mutations in the CLN6 gene cause variant late-onset infantile neuronal ceroid lipofuscinosis (vLINCL), a lysosomal storage disorder marked by progressive mental deterioration and blindness; part of a group of severe inherited neurodegenerative disorders affecting children wherein lysosomes accumulate storage material, causing the death of neurons. CLN6 is one of eight proteins, including CLN1-8, that are associated with NCL.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CLN6
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene CLN6
Gene Accession No. Q9NWW5
Gene Alias 1810065L06Rik; AW743417; ceroid-lipofuscinosis; ceroid-lipofuscinosis neuronal 6 late infantile; ceroid-lipofuscinosis neuronal protein 6; ceroid-lipofuscinosis, neuronal 6; ceroid-lipofuscinosis, neuronal 6, late infantile, variant; CLN4A; CLN6; D9Bwg1455e; HsT18960; nclf; neuronal ceroid lipofuscinosis; Protein CLN6
Gene Symbols CLN6
Host Species Rabbit
Immunogen A synthesized peptide derived from human CLN6(Accession Q9NWW5), corresponding to amino acid residues V225-L275.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 315746, 54982, 76524
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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