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  7. Thermo Scientific Chemicals Cinchonidine, 98.5-101%

Thermo Scientific Chemicals Cinchonidine, 98.5-101%

Product Code. 10755751 Shop All Thermo Scientific Chemicals Products
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Product Code. 10755751 Supplier Thermo Scientific Chemicals Supplier No. 110331000
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Description

Cinchonidine, CAS # 485-71-2, is a naturally occurring alkaloid that may be used in asymmetric synthesis and exhibits anti-malarial activity | CAS: 485-71-2 | C19H22N2O | 294.40 g/mol

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • Cinchonidine is an alkaloid naturally occurring in the bark of Cinchona strubs that has activity against Plasmodium spp
  • Cinchonidine is a diastereoisomer of cinchonine and can be used to promote chirality in asymmetric or enantioselective synthesis of organic compounds

Applications

  • Cinchonidine has been used as a starting material in the synthesis of anti-malarial cinchona alkaloid conjugates
  • Has been shown to potently induce γ-globin mRNA and fetal hemoglobin in erythroid progenitor cells and may be useful in preclinical studies of β-thalassemia
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 485-71-2
Molecular Formula C19H22N2O
Molecular Weight (g/mol) 294.40
MDL Number MFCD00006783
InChI Key KMPWYEUPVWOPIM-UHFFFAOYNA-N
Synonym cinchonidine
PubChem CID 45358337
IUPAC Name [(2R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-quinolin-4-ylmethanol
SMILES OC(C1CC2CCN1CC2C=C)C1=C2C=CC=CC2=NC=C1

Specifications

Melting Point 200.0°C to 203.0°C
Color White to Cream
Loss on Drying 1% max. (105°C)
Infrared Spectrum Authentic
Assay Percent Range 98.5-101%
Packaging Glass bottle
Quantity 100 g
Beilstein 23, 420
Merck Index 15, 2289
Specific Rotation − 115.00
Solubility Information Solubility in water: insoluble. Other solubilities: soluble in alcohol and chloroform
Formula Weight 294.39
Percent Purity 98.5-101%
Physical Form Crystalline Powder
Chemical Name or Material Cinchonidine, 98.5-101%
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