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STEMCELL Technologies CHIR98014

Product Code. 17160162
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Product Code. 17160162 Supplier STEMCELL Technologies Supplier No. 73044

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WNT pathway activator; Inhibits GSK3α and GSK3β

  • CHIR98014 is a reversible, cell-permeable activator of the WNT pathway, through inhibition of both isoforms of glycogen synthase kinase 3 (GSK3α and GSK3β) with IC50 values of 0.65 and 0.58 nM, respectively
  • It shows at least 500-fold selectivity for GSK-3 versus 20 other serine/threonine or tyrosine kinases (Ring et al.)

Specifications

CAS 556813-39-9
Quantity 10 mg
Molecular Formula C20H17Cl2N9O2
Purity ≥98%
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