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  8. CGS 15943, Tocris Bioscience™

CGS 15943, Tocris Bioscience™

Catalog Number 18084132
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
104615-18-1
C13H8ClN5O
285.69
MFCD01529897
MSJODEOZODDVGW-UHFFFAOYSA-N
9-chloro-2-2-furyl-1,2,4 triazolo 1,5-c quinazolin-5-imine, 9-chloro-2-furan-2-yl-1,2,4 triazolo 1,5-c quinazolin-5-amine, chembl16687, 9-chloro-2-2-furyl 1,2,4 triazolo 1,5-c quinazolin-5-amine, 1,2,4 triazolo 1,5-c quinazolin-5-amine,9-chloro-2-2-furanyl, 9-chloro-2-2-furanyl-1,2,4 triazolo 1,5-c quinazolin-5-amine, 1,2,4 triazolo 1,5-c quinazolin-5-amine, 9-chloro-2-2-furanyl, acmc-20ddlj
2690
9-chloro-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5-amine
NC1=NC2=CC=C(Cl)C=C2C2=NC(=NN12)C1=CC=CO1
This item is not returnable. View return policy
104615-18-1
C13H8ClN5O
285.69
MFCD01529897
MSJODEOZODDVGW-UHFFFAOYSA-N
9-chloro-2-2-furyl-1,2,4 triazolo 1,5-c quinazolin-5-imine, 9-chloro-2-furan-2-yl-1,2,4 triazolo 1,5-c quinazolin-5-amine, chembl16687, 9-chloro-2-2-furyl 1,2,4 triazolo 1,5-c quinazolin-5-amine, 1,2,4 triazolo 1,5-c quinazolin-5-amine,9-chloro-2-2-furanyl, 9-chloro-2-2-furanyl-1,2,4 triazolo 1,5-c quinazolin-5-amine, 1,2,4 triazolo 1,5-c quinazolin-5-amine, 9-chloro-2-2-furanyl, acmc-20ddlj
2690
9-chloro-2-(furan-2-yl)-[1,2,4]triazolo[1,5-c]quinazolin-5-amine
NC1=NC2=CC=C(Cl)C=C2C2=NC(=NN12)C1=CC=CO1

Description

Potent adenosine receptor antagonist

CGS 15943 is a potent adenosine receptor antagonist (Ki values are 3.5, 4.2, 16 and 51 nM for human A1, A2A, A2B and A3 receptors respectively). Inhibits the catalytic subunit of the class IB PI3K isoform p110γ (IC50 = 1.1 μM). Blocks HCC and HDAC cell proliferation in vitro via inhibition of the PI3K/Akt pathway; reduces proliferation of ER+ breast cancer cells. Also acts as a BMP-4 mimetic to stimulate osteogenic differentiation. Orally active in vivo.
Quantity 50 mg
Formula Weight 285.69
Percent Purity >99%
Chemical Name or Material CGS 15943
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