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Invitrogen™ CERKL Polyclonal Antibody

Description
Peptide sequence: ASVKNQFNFP FVETYTVEEV KVHPRNNTGG YNPEEEEDET ASENCFPWNV Sequence homology: Dog: 90%; Guinea Pig: 79%; Horse: 79%; Human: 100%; Mouse: 79%; Rabbit: 81%; Rat: 79%; Yeast: 89%; Zebrafish: 79%.
This gene was initially identified as a locus (RP26) associated with an autosomal recessive form of retinitis pigmentosa (arRP) disease. This gene encodes a protein with ceramide kinase-like domains, however, the protein does not phosphorylate ceramide and its target substrate is currently unknown. This protein may be a negative regulator of apoptosis in photoreceptor cells. Mutations in this gene cause a form of retinitis pigmentosa characterized by autosomal recessive cone and rod dystrophy (arCRD). Alternative splicing of this gene results in multiple transcript variants encoding different isoforms and non-coding transcripts.[provided by RefSeq, May 2010].
Specifications
Specifications
| Antigen | CERKL |
| Applications | Western Blot |
| Classification | Polyclonal |
| Concentration | 0.5 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 2% sucrose and 0.09% sodium azide |
| Gene | CERKL |
| Gene Accession No. | Q49MI3 |
| Gene Alias | ceramide kinase like; ceramide kinase-like; ceramide kinase-like protein; CERKL; Gm1958; retinitis pigmentosa 26 (autosomal recessive); Rp26; zgc:162213 |
| Gene Symbols | CERKL |
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