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Cefotaxime sodium salt

Código de producto. 15485009
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Código de producto. 15485009 Proveedor Thermo Scientific Alfa Aesar N.º de proveedor J62690.06
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Cefotaxime sodium salt, CAS # 64485-93-4, is the sodium salt form of cefotaxime with β-lactamase resistant antibiotic activity. | CAS: 64485-93-4 | C16H16N5NaO7S2 | 477.44 g/mol

Cefotaxime sodium salt acts as a beta-lactamase resistant antibiotic. It is used as an effective antibacterial against gram-negative bacteria, with the notable exception of pseudomonas and penicillin-resistant strains of streptococcus pneumoniae. It is used to treat infections of the bones, joints, skin, respiratory tract and blood stream.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Information

• The cefotaxime sodium salt is a - lactamase considered a third-generation cephalosporin with antibiotic and bactericidal activities
• This compound exerts its biological activity by binding to penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall leading to their inactivation. The inactivation of these proteins affects the cross-linking of peptidoglycan chains required for bacterial cell wall strength and rigidity, resulting in the weakening of cell walls and cell lysis.

Applications

• It is an efficient antibacterial compound that acts against gram-negative bacteria, without activity against gram-positive bacteria such as pseudomonas and penicillin-resistant strains of streptococcus pneumonia
• It has been used for plant cell culture and human cell lines in vitro
• Cefotaxime sodium salt has been used in antibiotic susceptibility testing (AST) methods
• Cefotaxime sodium salt is also used to remove bacteria from Ostreococcus tauri cultures

TRUSTED_SUSTAINABILITY

Identificadores de productos químicos

CAS 64485-93-4
Molecular Formula C16H16N5NaO7S2
Molecular Weight (g/mol) 477.44
MDL Number MFCD00079073
InChI Key AZZMGZXNTDTSME-JUZDKLSSSA-M
PubChem CID 88631411
IUPAC Name sodium (6R,7R)-3-[(acetyloxy)methyl]-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
SMILES [Na+].CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(COC(C)=O)=C(N2C1=O)C([O-])=O)C1=CSC(N)=N1

Especificaciones

Type Cefotaxime Sodium Salt
Physical Form Powder
Color White to Yellow
Quantity 5 g
Beilstein 5711411
Merck Index 14,1933
Solubility Information Soluble in water.
Formula Weight 477.4
Chemical Name or Material Cefotaxime sodium salt
compliance-icons compliance-icons
Nombre del producto
  • Cefotaxime sodium salt
Palabra de advertencia
  • Danger
Clasificación
  • Serious eye damage/eye irritation Category 2
  • Respiratory sensitiser Category 1
  • Skin corrosion/irritation Category 2
  • Skin sensitiser Category 1
  • Specific target organ toxicity Category 3
Indicaciones de peligro
  • H315-Causes skin irritation.
  • H317-May cause an allergic skin reaction.
  • H319-Causes serious eye irritation.
  • H334-May cause allergy or asthma symptoms or breathing difficulties if inhaled.
  • H335-May cause respiratory irritation.
Consejos de prudencia
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P302+P352-IF ON SKIN: Wash with plenty of water/soap.
  • P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P312-Call a POISON CENTER/doctor/if you feel unwell.
Otros peligros
  • MIXTURE LIST-Contain: Sodium [6R-[6.alpha.,7.beta.(Z)]]-3-(acetoxymethyl) -7-[(2-aminothiazol-4-yl)(methoxyimino)acet amid

RUO – Research Use Only

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