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Cefotaxime Sodium Salt, MP Biomedicals™
BIOPHARMA

Product Code. 11419101 Shop All MP Biomedicals Products
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Quantity:
1 g
Unit Size:
1g
Product Code. Quantity unitSize
11419101 1 g 1g
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Product Code. 11419101

Brand: MP Biomedicals 0215494791

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Description

Inhibits bacterial cell wall synthesis. Cefotaxime Sodium Salt, MP Biomedicals is a cephalosporin antibiotic that is active against both gram-negative and gram-positive bacteria. It is used for infections of the respiratory tract, skin, bones, joints, uro

Cefotaxime binds to penicillin-binding proteins (PBPs), which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. As a result, bacteria lyse due to cell wall autolytic enzymes. Cefotaxime blocks the division of cyanobacteria and lower plant organelles/plastids such as the photosynthetic organelles of Glaucophytes and chloroplasts of bryophytes. Cefotaxime is used to treat a variety of bacterial infections:

  • Good coverage against most Gram-negative bacteria, with the notable exception of Pseudomonas
  • Effective against most Gram-positive cocci, except for Enterococcus
  • Active against penicillin-resistant strains of Streptococcus pneumoniae
  • Modest activity against the anaerobic Bacteroides fragilis
  • In meningitis, cefotaxime crosses the blood–brain barrier better than cefuroxime
TRUSTED_SUSTAINABILITY

Specifications

Physical Form Powder
CAS 64485-93-4
Quantity 1 g
Molecular Formula C16H16N5NaO7S2
MDL Number MFCD00079073
Synonym Cefotaxime sodium, (6R-(6-a,7-b(Z)))-3-((Acetyloxy) methyl)-7- (((2-amino-4-thiazolyl) (methoxyimio) acetyl) amino)-8- oxo-5-thia-1- azabicyclo (4,2,0) oct-2-ene-2-carboxylic acid, sodium salt
Solubility Information Soluble in water (0.05gm/1mL, clear, light yellow solution).
InChI Key AZZMGZXNTDTSME-JUZDKLSSSA-M
SMILES [Na+].CO\N=C(/C(=O)N[C@H]1[C@H]2SCC(COC(C)=O)=C(N2C1=O)C([O-])=O)C1=CSC(N)=N1
IUPAC Name sodium;(6S,7R)-3-(acetyloxymethyl)-7-[[2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
Molecular Weight (g/mol) 477.44
PubChem CID 88631411
Formula Weight 477.45
Percent Purity ≥95%
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Safety and Handling

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Product Identifier
  • Cefotaxime Sodium Salt
 Signal Word
  • Danger
 Hazard Category
  • Respiratory sensitiser Category 1
  • Skin sensitiser Category 1
 Hazard Statement
  • H317-May cause an allergic skin reaction.
  • H334-May cause allergy or asthma symptoms or breathing difficulties if inhaled.
 Precautionary Statement
  • P101-If medical advice is needed, have product container or label at hand.
  • P102-Keep out of reach of children.
  • P103-Read label before use.
  • P261-Avoid breathing dust/fume/gas/mist/vapours/spray.
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P284-¢In case of inadequate ventilation! wear respiratory protection.
  • P321-Specific treatment (see on this label).
  • P342+P311-If experiencing respiratory symptoms: Call a POISON CENTER/doctor/ .
  • P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
 Supplemental information
  • MIXTURE LIST-Contains : Cefotaxime Sodium Salt
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