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Invitrogen™ CD66 Chimeric Recombinant Rabbit Monoclonal Antibody (A5B7)

Product Code. 17931661
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Quantity:
200 μg
Unit Size:
200µg
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17931661 200 μg 200µg
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Product Code. 17931661 Supplier Invitrogen™ Supplier No. MA548181

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Description

Rabbit Recombinant Monoclonal Antibody

Specificity: This antibody is specific for human CEA.

The CD66 molecules are 180-200 kDa glycoproteins of carcinoembryonic antigen family. They are present on all blood granulocytes and some tissue macrophages, but are absent from other hematopoietic cells. The expression of CD66 increases significantly on granulocytes upon their activation. CD66a (BGP1, CEACAM1) and CD66d (CGM1, CEACAM3), as well as CEACAM2 and 4, are transmembrane proteins, whereas CD66c (CEAL, NCA, CEACAM6) and CD66e (CEA, CEACAM5), as well as CEACAM7 and 8, are anchored to the plasma membrane by C-terminal glycosylphosphatidylinositol (GPI) lipid moiety.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD66 Chimeric
Applications Functional Assay, Immunohistochemistry, Radioimmune Assays (RIA)
Classification Recombinant Monoclonal
Clone A5B7
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% ProClin 300
Gene CEACAM1
Gene Accession No. O75871, P06731, P13688, P40198, P40199
Gene Alias antigen CD66; BGP; BGP1; BGP-1; BGPI; Biliary glycoprotein 1; Carcinoembryonic antigen; Carcinoembryonic antigen CGM1; carcinoembryonic antigen CGM7; carcinoembryonic antigen gene family member 1; carcinoembryonic antigen gene family member 7; carcinoembryonic antigen related cell adhesion molecule 1; carcinoembryonic antigen related cell adhesion molecule 3; carcinoembryonic antigen related cell adhesion molecule 4; carcinoembryonic antigen related cell adhesion molecule 5; carcinoembryonic antigen related cell adhesion molecule 6; carcinoembryonic antigen-related cell adhesion molecule 1; carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein); carcinoembryonic antigen-related cell adhesion molecule 3; Carcinoembryonic antigen-related cell adhesion molecule 4; carcinoembryonic antigen-related cell adhesion molecule 4-sv1; carcinoembryonic antigen-related cell adhesion molecule 4-sv2; carcinoembryonic antigen-related cell adhesion molecule 5; Carcinoembryonic antigen-related cell adhesion molecule 6; carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen); CD66a; CD66a antigen; CD66c; CD66d; CD66d antigen; CD66e; CEA; CEACAM1; CEACAM-1; CEACAM3; CEACAM-3; CEACAM4; CEACAM5; CEACAM-5; CEACAM6; CEACAM-6; CEAL; CGM1; CGM7; CGM7_HUMAN; Cluster of Differentiation 66c; meconium antigen 100; NCA; Non-specific crossreacting antigen; nonspecific cross-reacting antigen; Nonspecific cross-reacting antigen (NCA); non-specific cross-reacting antigen W236; nonspecific cross-reacting antigen W236; normal cross-reacting antigen; pan CEACAM; W264; W282
Gene Symbols CEACAM1, CEACAM3, CEACAM4, CEACAM5, CEACAM6
Host Species Rabbit
Immunogen This antibody was raised by immunising mice with both carcinoembryonic antigen (CEA) purified from the metastases of colonic tumours, and heat-treated CEA.
Purification Method Protein A
Quantity 200 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1048, 1084, 1089, 4680, 634
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG κ
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