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CD3e Hamster, anti-Mouse, PE, Clone: 145-2C11, STEMCELL Technologies
Hamster Monoclonal Antibody
Brand: Stemcell Technologies 60015PE.1
This item is not returnable.
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Description
- The 145-2C11 antibody reacts with the ∼20 kDa CD3ε subunit of the mouse T cell receptor (TCR)/CD3 complex, which is expressed on the surface of circulating mature T cells and NKT cells, and variably on thymocytes
- A majority of T cell neoplasms also express CD3
- Activation of T cells by the TCR involves the cytoplasmic tails of the CD3 subunits, which are structurally related type 1 transmembrane proteins and members of the immunoglobulin superfamily
- The 145-2C11 antibody has been used for in vitro functional (blocking and activation) assays and has been reported to block binding by the clone 17A2 antibody
- The 145-2C11 antibody is not recommended for use with formalin-fixed, paraffin-embedded sections
- This antibody clone has been verified for purity assessments of cells isolated with EasySep™ kits, including EasySep™ Mouse T Cell Isolation Kit (Catalog #19851) and EasySep™ Mouse CD90.2 Positive Selection Kit II (Catalog #18951)
Specifications
| CD3e | |
| Monoclonal | |
| PE | |
| 50 μg | |
| Mouse | |
| T Cells |
| Immunohistochemistry, Western Blot, ELISA, Flow Cytometry, Immunocytochemistry | |
| 145-2C11 | |
| Hamster | |
| Primary | |
| IgG1 κ |
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