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CD360 (IL-21 Receptor) Mouse anti-Human, PE, Clone: 2SX21R, eBioscience™

Mouse Monoclonal Antibody

Marke:  Affymetrix eBioscience 12-3601-42

Weitere Details : Gewicht : 0.23750kg

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Artikelnummer. 15526976

  • 281.00 € / 100 Tests


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von Anbieter 23-03-2020
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Beschreibung

Beschreibung

Excitation: 488-561 nm; Emission: 578 nm; Laser: Blue Laser, Green Laser, Yellow-Green Laser. Filtration: 0.2 μm post-manufacturing filtered. The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2 (IL2) and interleukin 5 (IL5). This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants encoding the same protein have been described.
Spezifikation

Spezifikation

CD360 (IL-21 Receptor)
Monoclonal
5 μL/Test
PBS with 0.1% gelatin, 0.2% BSA and 0.09% sodium azide; pH 7.2
Q9HBE5
Interleukin-21 Receptor
Mouse
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Flow Cytometry
2SX21R
PE
IL21R
Liquid
IL21R
IgG1, kappa
100 Tests
4° C, store in dark, DO NOT FREEZE!
Primary
50615
Videos
Dokumentation

For Research Use Only.