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PeproTech CD267 (TACI) Polyclonal Antibody, PeproTech®, Invitrogen™
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Product Code. 17834383
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17834383 100 μg 100µg
17804173 50 μg 50µg
17813993 1 mg 1mg
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Product Code. 17834383 Supplier PeproTech Supplier No. 500P166G100UG

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Description

Goat Polyclonal Antibody

AA Sequence of recombinant protein: SGLGRSRRGG RSRVDQEERF PQGLWTGVAM RSCPEEQYWD PLLGTCMSCK TICNHQSQRT CAAFCRSLSC RKEQGKFYDH LLRDCISCAS ICGQHPKQCA YFCENKLRSP VNLPPELRRQ RSGEVENNSD NSGRYQGLEH RGSEASPALP GLKLSADQV. Preparation: Produced from sera of goats immunized with highly pure Recombinant Human TACI. Anti-Human TACI-specific antibody was purified by affinity chromatography employing an immobilized Human TACI matrix. Sandwich ELISA: To detect Human TACI by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.5-2.0 μg/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with PeproTech Biotinylated Anti-Human TACI (500-P166GBt) as a detection antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human TACI. Western Blot: To detect Human TACI by Western Blot analysis this antibody can be used at a concentration of 0.1- 0.2 μg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant Human TACI is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.

Members in the TNF superfamily regulate immune responses and induce apoptosis. Two novel members in the TNF family were recently identified and designated BAFF/BLyS/TALL-1/THANK/zTNF4 and April/TALL-2, respectively. BAFF was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion. April regulates immunological and non-immunological cell growth. Three receptors, BCMA, TACI, and BAFF-R, for BAFF and April were recently identified. TACI, like BCMA, binds BAFF and April. TACI and its ligands regulate humoral immune responses, activate NF-kappa-B and c-jun N-terminal kinase, and are involved in B cell associated autoimmune diseases.
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Specifications

Antigen CD267 (TACI)
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.1-1.0 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene TNFRSF13B
Gene Accession No. O14836
Gene Alias 1200009E08Rik; CD267; CVID; CVID2; IGAD2; NEWGENE_1595998; RYZN; TACI; TNF receptor superfamily member 13B; Tnfrsf13b; TNFRSF14B; transmembrane activator and calcium-modulating and cyclophilin ligand interactor; transmembrane activator and CAML interactor; tumor necrosis factor receptor 13B; tumor necrosis factor receptor superfamily member 13B; tumor necrosis factor receptor superfamily, member 13B
Gene Symbols TNFRSF13B
Host Species Goat
Immunogen E.coli-derived Recombinant Human TACI.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 23495
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Lyophilized
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