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CD23 Mouse anti-Human, PE, Clone: M-L233, BD
Mouse Monoclonal Antibody
235.00 € - 427.00 €
Specifications
| Antigen | CD23 |
|---|---|
| Clone | M-L233 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Conjugate | PE |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
15891319
|
BD Biosciences
561774 |
25 Tests |
235.00 €
Each |
Estimated Shipment: 08-07-2024 Log in to see stock. |
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|
15868378
|
BD Biosciences
555711 |
100 Tests |
427.00 €
Each |
Estimated Shipment: 08-07-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
The M-L233 antibody specifically binds to human CD23, the low affinity receptor for human IgE (FcεRII). CD23 is a type II membrane glycoprotein that can be expressed by B cells, monocytes, macrophages, eosinophils, platelets and dendritic cells. CD23 can mediate IgE-dependent cytotoxicity and phagocytosis by macrophages and eosinophils. Soluble CD23 (sCD23) can be released by CD23-positive cells as a result of proteolytic cleavage of membrane CD23. Larger fragments of sCD23 (e.g., 25-37 kDa) retain their IgE-binding capacity whereas smaller fragments (i.e., ≤ 12 kDa) do not. Soluble CD23 may have immunoregulatory effects on the growth and differentiation of B cells and other cell types.
This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.
Specifications
| CD23 | |
| Flow Cytometry | |
| PE | |
| RUO | |
| Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
| M-L233 | |
| Monoclonal | |
| Mouse | |
| Human | |
| IgG1 κ | |
| Affinity Purified |
For Research Use Only.