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CD122 Rat anti-Mouse, Clone: TM-b1 (TM-beta1), eBioscience™

Rat Monoclonal Antibody

Marke:  Affymetrix eBioscience 14-1222-85

Weitere Details : Gewicht : 0.01000kg

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Artikelnummer. 15237197

  • 197.00 € / 500 Mikrogramm


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Beschreibung

Beschreibung

CD122 (Interleukin 2 receptor) is involved in T cell-mediated immune responses, primarily expressed in the hematopoietic system and is present in 3 forms. The low affinity form of CD122 is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from CD122. The protein encoded by the CD122 gene represents the beta subunit and is a type I membrane protein. Diseases associate with CD122 protein dysfunction include oligoarticular juvenile idiopathic arthritis and rheumatoid factor negative juvenile idiopathic arthritis.
Spezifikation

Spezifikation

CD122
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
P16297
CD122, IL15RB, P70-75, CD122 antigen, IL-2 receptor subunit beta, IL-2R subunit beta, IL-2RB, high affinity IL-2 receptor beta subunit, high affinity IL-2 receptor subunit beta, interleukin 15 receptor, beta, interleukin-2 receptor subunit beta, p75
Rat
Affinity chromatography
RUO
Antibody
Monoclonal
Mouse
Flow Cytometry, Functional Assay, Immunoprecipitation, Neutralization
TM-b1 (TM-beta1)
Unconjugated
Il2rb
Liquid
Il2rb
IgG2b, kappa
500 μg
4° C
Primary
16185
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