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CCT128930, MedChemExpress
Description
CCT128930 is a ATP-competitive and selective inhibitor of AKT (IC50=6 nM for AKT2). CCT128930 has 28-fold selectivity over the closely related PKA kinase (IC50=168 nM) through the targeting of Met282 of AKT (Met173 of PKA-AKT chimera), as well as 20-fold selectivity over p70S6K (IC50=120 nM). Antitumor activity.
Specifications
Specifications
| Chemical Name or Material | CCT128930 |
| CAS | 885499-61-6 |
| Color | Off-White |
| Purity Grade Notes | Research |
| Molecular Formula | C18H20ClN5 |
| Quantity | 10 mg |
| Solubility Information | DMSO : 33.33 mg/mL (97.50 mM; ultrasonic and warming and heat to 60°C) |
| SMILES | ClC1=CC=C(C=C1)CC2(CCN(CC2)C3=NC=NC4=C3C=CN4)N |
| Molecular Weight (g/mol) | 341.84 |
| Formula Weight | 341.84 |
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Research purposes only
Product Title
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