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Invitrogen™ CAS Recombinant Rabbit Monoclonal Antibody (1W4T4)

Rabbit Recombinant Monoclonal Antibody
Brand: Invitrogen™ MA537829
This item is not returnable.
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Description
Positive Samples: HeLa, 293T, Jurkat, Mouse testis, Mouse thymus Immunogen sequence: LIGLFELPED DTIPDEEHFI DIEDTPGYQT AFSQLAFAGK KEHDPVGQMV NNPKIHLAQS LHKLSTACPG RVPSMVSTSL NAEALQYLQG YLQAASVTLL.
Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation.
Specifications
| CAS | |
| Recombinant Monoclonal | |
| 0.5 mg/mL | |
| PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3 | |
| P55060, Q9ERK4 | |
| CSE1L | |
| A synthetic peptide corresponding to a sequence within amino acids 872-971 of human Exportin 2 (XPO2) (P55060). | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
| ELISA, Western Blot | |
| 1W4T4 | |
| Unconjugated | |
| CSE1L | |
| 2610100P18Rik; AA407533; Capts; CAS; Cellular apoptosis susceptibility protein; chromosome segregation 1 like; chromosome segregation 1-like (S. cerevisiae); chromosome segregation 1-like protein; CSE1; CSE1 chromosome segregation 1 like; CSE1 chromosome segregation 1-like; CSE1 chromosome segregation 1-like (yeast); CSE1L; Exp2; exportin-2; Importin-alpha re-exporter; MGC117283; MGC130036; MGC130037; XPO2 | |
| Rabbit | |
| Affinity Chromatography | |
| RUO | |
| 110750, 1434 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
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