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Description
Immunogen sequence: ILQALHECLA ALPRPQLRSV VGIGVSGQMH GVVFWKTGQG CEWTEGGITP VFEPRAVSHL VTWQDGRCSS EFLASLPQPK SHLSVATGFG CATIFWLLKY R Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 79%.
The protein encoded by this gene has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibiting return across the cell membrane. Sequence variation between this novel gene and known carbohydrate kinases suggests the possibility of a different substrate, cofactor or changes in kinetic properties distinguishing it from other carbohydrate kinases. The gene resides in a region commonly deleted in cystinosis patients, suggesting a role as a modifier for the cystinosis phenotype. The genomic region is also rich in Alu repetitive sequences, frequently involved in chromosomal rearrangements.
Specifications
Specifications
| Antigen | CARKL |
| Applications | Immunohistochemistry (Paraffin), Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 0.05 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 40% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | SHPK |
| Gene Accession No. | Q9UHJ6 |
| Gene Alias | 4930431K22Rik; AI194947; AW260459; Carbohydrate kinase-like protein; CARKL; Sedoheptulokinase; SHK; Shpk |
| Gene Symbols | SHPK |
| Show More |
Product Title
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