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Invitrogen™ CARD11 Monoclonal Antibody (B.472.3)

Description
It is not recommended to aliquot this antibody.
The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.
Specifications
Specifications
| Antigen | CARD11 |
| Applications | Western Blot |
| Classification | Monoclonal |
| Clone | B.472.3 |
| Concentration | 344 μg/mL |
| Conjugate | Unconjugated |
| Formulation | 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and <0.02% sodium azide; pH 7.5 |
| Gene | CARD11 |
| Gene Accession No. | Q8CIS0, Q9BXL7 |
| Gene Alias | 0610008L17Rik; 2410011D02Rik; bcl10-interacting maguk protein 3; BENTA; BIMP3; Card11; CARD-containing MAGUK protein 1; Carma 1; CARMA1; caspase recruitment domain family member 11; caspase recruitment domain family, member 11; caspase recruitment domain-containing protein 11; IMD11; LOC100363332; MGC133069; PPBL |
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