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Description
Carbenicillin is a semi-synthetic antibiotic that is an analog to ampicillin. It is derived from benzyl penicillin by substituting the a-carboxyl group in the benzyl side chain. It is completely ionized in the blood and is about 50% reversibly protein bound in plasma. Its tissue distribution is similar to other penicillins.
Susceptible bacteria include gram-positive and gram-negative bacteria abd pseudomonas.Though it has substantial in vitro activity against a variety of both gram-positive and gram-negative microorganisms, the most important aspect of its profile is in its antipseudomonal and antiproteal effect.
Carbenicillin Disodium Salt is used for selection of ampr transformed cells and to study the role of penicillin-sensitive transpeptidases in cell wall biosynthesis.
Specifications
Specifications
| Physical Form | Powder |
| CAS | 4800-94-6 |
| Potency | >650μg/mg |
| Color | White |
| Concentration | Working Concentration: 105u/L (5-50μg/mL) in cell culture; approximately 200mg/kg in vivo. |
| Quantity | 250 mg |
| Molecular Formula | C17H16N2Na2O6S |
| MDL Number | MFCD00077683 |
| Synonym | α-Carboxybenzylpenicillin |
| Solubility Information | Soluble in water (50mg/mL) and alcohol |
| Vedi altri risultati |
Sicurezza e movimentazione
- Carbenicillin Disodium Salt
- Danger
- Respiratory sensitiser Category 1
- Skin sensitiser Category 1
- H317-May cause an allergic skin reaction.
- H334-May cause allergy or asthma symptoms or breathing difficulties if inhaled.
- P260-Do not breathe dust/fume/gas/mist/vapours/spray.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P321-Specific treatment (see on this label).
- P501b-Dispose of contents/container in accordance with local/regional/national/international regulations.
- MIXTURE LIST-Contain: Carbenicillin Disodium Salt
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