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Invitrogen™ C1QBP Monoclonal Antibody (74.5.2)

Description
The monoclonal antibody 74.5.2 is directed against epitopes in the XC15 peptide that contains a binding site for high-molecular-weight kininogen and Factor XII. Clone 74.5.2 recognizes both the mature (74-282) and truncated form, lacking residues 74-95.
Replication Protein A (RPA) (also known as human single-stranded DNA binding protein, or HSSB) is involved in DNA replication, repair, and recombination. RPA from human cells is a stable heterotrimer of 70kDa, 32-34kDa, and 11-14kDa subunits (RPA70, RPA32, and RPA14 respectively). RPA is required for the SV40 large tumor antigen-catalyzed unwinding of SV40 DNA and stimulates DNA polymerase alpha and delta. RPA34 is phosphorylated at the G1/S boundary of the cell cycle or upon exposure of cells to DNA damage-inducing agents including ionizing and UV radiation.
Specifications
Specifications
| Antigen | C1QBP |
| Applications | Flow Cytometry, Functional Assay, Inhibition Assays, Immunoprecipitation, Western Blot, Immunocytochemistry |
| Classification | Monoclonal |
| Clone | 74.5.2 |
| Concentration | 100 μg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 0.1% BSA and no preservative |
| Gene | C1QBP |
| Gene Accession No. | Q07021 |
| Gene Alias | AA407365; AA986492; ASF/SF2-associated protein p32; C1q globular domain-binding protein; C1QBP; complement C1q binding protein; complement component 1 Q subcomponent-binding protein, mitochondrial; complement component 1, q subcomponent binding protein; D11Wsu182e; GC1QBP; gC1qR; gC1Q-R; gC1q-R protein; glycoprotein gC1qBP; HABP1; Hyaluronan-binding protein 1; mitochondrial matrix protein p32; p32; p33; RPA; SF2AP32; SF2p32; splicing factor SF2-associated protein |
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