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Tocris Bioscience™ Brefeldin A

Product Code. 18055762
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5 mg
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5mg
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Product Code. 18055762 Supplier Tocris Bioscience™ Supplier No. 1231/5

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208.20 EUR valid until 2026-03-31
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Description

Disrupts protein translocation to Golgi

Reversible inhibitor of protein translocation from the endoplasmic reticulum (ER) to the Golgi apparatus. Blocks binding of ADP-ribosylation factor (ARF1) to the Golgi apparatus and inhibits GDP-GTP exchange. Can be used to induce autophagy in mammalian cells. Also enhances CRISPR-mediated homology-directed repair (HDR) efficiency ∼2-fold when applied at 100 nM, in human induced pluripotent stem cells (iPSCs). Antifungal.
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Specifications

CAS 20350-15-6
Quantity 5 mg
Molecular Formula C16H24O4
Formula Weight 280.36
Purity >98%
Molecular Weight (g/mol) 280.36
Chemical Name or Material 1,6,7,8,9,11 Aβ,12,13,14,14 Aα-Decahydro-1β,13α-dihydroxy-6β-methyl-4 H-cyclopent[f]oxacyclotridecin-4-one
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