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BMS 777607, MedChemExpress

Product Code. 16497707
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Product Code. 16497707 Supplier Medchem Express Supplier No. HY12076

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Description

MedChemExpress BMS 777607 (BMS 817378) is a Met-related inhibitor for c-Met, Axl, Ron and Tyro3 with IC50s of 3.9 nM, 1.1 nM, 1.8 nM and 4.3 nM, respectively, and 40-fold more selective for Met-related targets than Lck, VEGFR-2, and TrkA/B, with more than 500-fold greater selectivity versus all other receptor and non receptor kinases.

BMS 777607 (BMS 817378) is a Met-related inhibitor for c-Met, Axl, Ron and Tyro3 with IC50s of 3.9 nM, 1.1 nM, 1.8 nM and 4.3 nM, respectively, and 40-fold more selective for Met-related targets than Lck, VEGFR-2, and TrkA/B, with more than 500-fold greater selectivity versus all other receptor and non receptor kinases.

Specifications

Chemical Name or Material BMS 777607
CAS 1025720-94-8
Color White
Purity Grade Notes Research
Molecular Formula C25H19ClF2N4O4
Quantity 5 mg
Synonym BMS 817378
Solubility Information DMSO : ≥ 39 mg/mL (76.04 mM)
SMILES O=C(NC1=CC=C(C(F)=C1)OC2=C(C(N)=NC=C2)Cl)C3=C(C=CN(C3=O)C4=CC=C(C=C4)F)OCC
Molecular Weight (g/mol) 512.89
Formula Weight 512.89
Percent Purity 98.49%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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