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  5. STEMCELL Technologies BMS 493

STEMCELL Technologies BMS 493

Product Code. 17140302
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Quantity:
1 mg
10 mg
Unit Size:
10mg
1mg
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Product Code. 17140302

Brand: STEMCELL Technologies 73972

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This item is not returnable. View return policy

Description

Retinoid pathway activator; Activates pan-retinoic acid receptor

  • BMS 493 is an inverse agonist of the pan-retinoic acid receptors (RARs)
  • RARs are ligand-dependent transcription factors that regulate gene networks that control cell growth, differentiation, survival, and death (Germain et al.) BMS 493 has been shown to increase nuclear receptor co-repressor (NCoR) interaction with RARs (Germain et al.; Rinkevich et al.)
  • Affects development of bronchial tubule formation in mice (Chazaud et al.)
  • Inhibits activation of immature dendritic cells (Geissmann et al.)
  • Inhibits differentiation of leukemic blasts (Kamashev et al.)

Specifications

CAS 215030-90-3
Synonym BMS 204493
Quantity 1 mg
Molecular Formula C29H24O2
Purity ≥98%
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