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Invitrogen™ BCL2L12 Polyclonal Antibody

Description
Antibody detects endogenous levels of total BCL2L12.
This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants.
Specifications
Specifications
| Antigen | BCL2L12 |
| Applications | Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 |
| Gene | BCL2L12 |
| Gene Accession No. | Q9HB09 |
| Gene Alias | 2810475P17Rik; 5430429M05Rik; BCL2 like 12; Bcl-2 related proline-rich protein; Bcl2l12; Bcl2-L12; Bcl2-L-12; BCL2-like 12 (proline rich); bcl-2-like protein 12; Bcl-2-related proline-rich protein; Bcl-L12; BPR |
| Gene Symbols | BCL2L12 |
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