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Tocris Bioscience™ BAY 390

Product Code. 30058518
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10 mg
Unit Size:
10mg
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30058518 10 mg 10mg
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Product Code. 30058518 Supplier Tocris Bioscience™ Supplier No. 7978/10

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305.20 EUR valid until 2026-03-31
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Description

Potent and selective TRPA1 antagonist. Brain penetrant and orally bioavailable

BAY 390 is a potent and selective transient receptor potential ankyrin 1 (TRPA1) antagonist (IC50 values are 16, 63 and 82 nM for hTRPA1 FLIPR, rTRPA1 FLIPR and hTRPA1 Ephys, respectively). In vivo, BAY 390 exhibits efficacy in rat models of inflammatory and neuropathic pain. BAY 390 is orally bioavailable and brain penetrant. Suitable to use as an in vitro or in vivo probe to investigate the roles of TRPA1 in models of acute, inflammatory, and neuropathic pain.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material (1R,2R)-2-[(4-Fluorophenyl)amino]-1-(trifluoromethyl)cyclohexanol
CAS 2741956-55-6
Quantity 10 mg
Target TRPA1 Blockers
Molecular Formula C13H15F4NO
Purity 0.98
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