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  6. BAIAP2L1 Rabbit anti-Human, Polyclonal, Proteintech

BAIAP2L1 Rabbit anti-Human, Polyclonal, Proteintech

Product Code. 16884255 Shop All Proteintech Products
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20 μL
150 μL
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150µL
20µL
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16884255 20 μL 20µL
16874255 150 μL 150µL
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Product Code. 16884255 Supplier Proteintech Supplier No. 256921AP20UL

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Description

Rabbit Polyclonal Antibody

This gene encodes a member of the IMD (IRSp53/MIM homology domain) family. Members of this family can be subdivided in two groups, the IRSp53-like and MIM-like, based on the presence or absence of the SH3 (Src homology 3) domain. The protein encoded by this gene contains a conserved IMD, also known as F-actin bundling domain, at the N-terminus, and a canonical SH3 domain near the C-terminus, so it belongs to the IRSp53-like group. This protein is the substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac. It is involved in signal transduction pathways that link deformation of the plasma membrane and remodeling of the actin cytoskeleton. It also promotes actin assembly and membrane protrusions when overexpressed in mammalian cells, and is essential to the formation of a potent actin assembly complex during EHEC (Enterohemorrhagic Escherichia coli) pedestal formation.

Specifications

Antigen BAIAP2L1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.27 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene BAIAP2L1
Gene Accession No. Q9UHR4
Gene Alias BAIAP2L1, IRTKS
Gene Symbols BAIAP2L1
Host Species Rabbit
Immunogen BAIAP2L1 Fusion Protein Ag22499
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55971
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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