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Bafetinib, MedChemExpress

Product Code. 16488118
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Product Code. 16488118

Brand: Medchem Express HY50868

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Description

MedChemExpress Bafetinib is a potent and orally active Lyn/Bcr-Abl tyrosine kinase inhibitor. Bafetinib augments the activities of several proapoptotic Bcl-2 homology (BH)3-only proteins (Bim, Bad, Bmf and Bik) and induces apoptosis in Ph+ leukemia cells via Bcl-2 family-regulated intrinsic apoptosis pathway.

Bafetinib is a potent and orally active Lyn/Bcr-Abl tyrosine kinase inhibitor. Bafetinib augments the activities of several proapoptotic Bcl-2 homology (BH)3-only proteins (Bim, Bad, Bmf and Bik) and induces apoptosis in Ph+ leukemia cells via Bcl-2 family-regulated intrinsic apoptosis pathway.

Specifications

Chemical Name or Material Bafetinib
Physical Form Solid
CAS 859212-16-1
Color Light Yellow
Quantity 10 mg
Purity Grade Notes Research
Molecular Formula C30H31F3N8O
For Use With (Application) Cancer-Kinase/protease
Synonym INNO-406 NS-187
Solubility Information DMSO : 100 mg/mL (173.42 mM; Need ultrasonic)
SMILES O=C(C1=CC=C(C(C(F)(F)F)=C1)CN2C[C@@H](N(C)C)CC2)NC3=CC=C(C)C(NC4=NC=CC(C5=CN=CN=C5)=N4)=C3
Molecular Weight (g/mol) 576.62
Formula Weight 576.62
Percent Purity 99.18%
Grade Research
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Research purposes only

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