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Tocris Bioscience™ AZD 9272
Potent and selective mGlu5 antagonist; brain penetrant
Brand: Tocris Bioscience™ 5613/50
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Description
AZD 9272 is a potent and selective mGlu5 antagonist (IC50 values are 2.6 and 7.6 nM for rat and human receptors, respectively). Exhibits >3900-fold selectivity for mGlu5 over other mGlu receptors. Also selective over a panel of other targets. Displays discriminative effects in rats. Orally bioavailable and brain penetrant.Specifications
| 3-Fluoro-5-[3-(5-fluoro-2-pyridinyl)-1,2,4-oxadiazol-5-yl]benzonitrile | |
| 327056-26-8 | |
| 50 mg |
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