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AZ1495, MedChemExpress

Product Code. 16495296
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Product Code. 16495296

Brand: Medchem Express HY111101

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Description

MedChemExpress AZ1495, a weak base, is a potent orally active interleukin-1 receptor associated kinase 4 (IRAK4) inhibitor. AZ1495 has a favorable physicochemical and kinase selectivity for IRAK4 and IRAK1 with IC50 values of 0.005 μM and 0.023 μM, respectively. AZ1495 has IRAK4 inhibition with a Kd value of 0.0007 μM. AZ1495 can be used for the research of diffuse large B-cell lymphoma (DLBCL).

AZ1495, a weak base, is a potent orally active interleukin-1 receptor associated kinase 4 (IRAK4) inhibitor. AZ1495 has a favorable physicochemical and kinase selectivity for IRAK4 and IRAK1 with IC50 values of 0.005 μM and 0.023 μM, respectively. AZ1495 has IRAK4 inhibition with a Kd value of 0.0007 μM. AZ1495 can be used for the research of diffuse large B-cell lymphoma (DLBCL).

Specifications

Chemical Name or Material AZ1495
Physical Form Solid
CAS 2196204-23-4
Color White
Quantity 100 mg
Purity Grade Notes Research
Molecular Formula C21H31N5O2
For Use With (Application) Cancer-Kinase/protease
Solubility Information DMSO : 10 mg/mL (25.94 mM; Need ultrasonic)
SMILES C1(C(C2CCOCC2)=CN3)=C3N=CN=C1N[C@@H]4CC[C@@H](N5CCOCC5)CC4
Molecular Weight (g/mol) 385.5
Formula Weight 385.5
Percent Purity 98.0%
Grade Research
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Research purposes only

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