missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Benzenoids
  6. Benzene and substituted derivatives
  7. Fluorobenzenes
  8. AX-024, MedChemExpress

AX-024, MedChemExpress

Product Code. 16470477
Encompass_Preferred
Change view
Click to view available options
Quantity:
2 mg
5 mg
10 mg
25 mg
50 mg
100 mg
Unit Size:
100mg
10mg
25mg
2mg
50mg
5mg
6 product options available for selection
Product selection table with 6 available options. Use arrow keys to navigate and Enter or Space to select.
Product Code. Quantity unitSize
16470477 50 mg 50mg
16482956 25 mg 25mg
16406827 5 mg 5mg
16405096 100 mg 100mg
16404128 10 mg 10mg
16400126 2 mg 2mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 6 options available.
6 options
This item is not returnable. View return policy
Product Code. 16470477 Supplier Medchem Express Supplier No. HY107390

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

MedChemExpress AX-024 is an orally available, first-in-class inhibitor of the TCR-Nck interaction that selectively inhibits TCR-triggered T cell activation with an IC50 ∼1 nM. AX-024 modulates cell signaling by targeting SH3 domains. AX-024 has low-acute toxicity and high potency and selectivity, and strongly inhibit the production of IL-6, TNF-α, IFN-γ, IL-10 and IL-17A.

AX-024 is an orally available, first-in-class inhibitor of the TCR-Nck interaction that selectively inhibits TCR-triggered T cell activation with an IC50 ∼1 nM. AX-024 modulates cell signaling by targeting SH3 domains. AX-024 has low-acute toxicity and high potency and selectivity, and strongly inhibit the production of IL-6, TNF-α, IFN-γ, IL-10 and IL-17A.

Specifications

Chemical Name or Material AX-024
CAS 1370544-73-2
Color Light Yellow
Purity Grade Notes Research
Molecular Formula C21H22FNO2
Quantity 50 mg
Solubility Information Ethanol : 100 mg/mL (294.64 mM; Need ultrasonic) ∣DMSO : 35 mg/mL (103.12 mM; Need ultrasonic and warming)
SMILES COC1=CC=C(OC2)C(C(C3=CC=C(F)C=C3)=C2CN4CCCC4)=C1
Molecular Weight (g/mol) 339.4
Formula Weight 339.4
Percent Purity 98.0%
Grade Research
Physical Form Powder
For Use With (Application) COVID-19-immunoregulation
Show More Show Less

Research purposes only

Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.