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AVN-944, MedChemExpress

Product Code. 16488427
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Product Code. 16488427 Supplier Medchem Express Supplier No. HY13560

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Description

MedChemExpress AVN-944 (VX-944) is an orally active, potent, selective, noncompetitive and specific inhibitor of IMPDH (inosine monophosphate dehydrogenase).

AVN-944 is an essential rate-limiting enzyme in de novo guanine nucleotide synthesis. AVN-944 is also an inhibitor of arenavirus RNA synthesis, and blocks arenavirus infection. AVN-944 has broad anti-cancer activities, and can be used for multiple myeloma (MM) and acute myeloid leukemia (AML) research.

Specifica

Chemical Name or Material AVN-944
CAS 297730-17-7
Color White
Purity Grade Notes Research
Molecular Formula C25H27N5O5
Quantity 5 mg
Synonym VX-944
Solubility Information DMSO : 100 mg/mL (209.42 mM; Need ultrasonic)
SMILES O=C(O[C@@H](CC#N)CC)N[C@H](C1=CC=CC(NC(NC2=CC=C(C3=CN=CO3)C(OC)=C2)=O)=C1)C
Molecular Weight (g/mol) 477.51
Formula Weight 477.51
Percent Purity 99.33%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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