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Thermo Scientific Chemicals Aurora Kinase/Cdk Inhibitor

Product Code. 15447179
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Product Code. 15447179 Supplier Thermo Scientific Chemicals Supplier No. J65997.#0
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Description

 

Aurora Kinase/Cdk Inhibitor is a broad spectrum inhibitor of cyclin-dependent kinases and aurora kinases including CDK1/Cyclin B, CDK2/Cyclin A, CDK2/Cyclin E, Aurora-A and Aurora-B. It as been shown to induce growth suppression and mitotic defects, these results suggest that Aurora Kinase/Cdk Inhibitor could be useful for cell cycle analysis and therapy of various cancers, including Ewing's sarcoma.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

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Specifications

Quantity 5 mg
Description White
Content And Storage 2°C to 8°C
For Use With (Application) A cell-permeable triazolylsulfonamido compound that acts a reversible, ATP-competitive kinase inhibitor with selectivities towards Aurora kinases
CAS 443797-96-4
Molecular Formula C15H12F2N6O3S.CH3CN, C15H12F2N6O3S
Formula Weight 435.41
Synonym 4-(5-Amino-1-(2,6-difluorobenzoyl)-1H-[1,2,4]triazol-3-ylamino)-benzenesulfonamide;
Sensitivity Light Sensitive
Solubility Soluble in DMSO at 15mg/ml
Product Type Aurora Kinase/Cdk Inhibitor
Form Powder
InChI Key KDKUVYLMPJIGKA-UHFFFAOYSA-N
SMILES NC1=NC(NC2=CC=C(C=C2)S(N)(=O)=O)=NN1C(=O)C1=C(F)C=CC=C1F
IUPAC Name 4-{[5-amino-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazol-3-yl]amino}benzene-1-sulfonamide
Molecular Weight (g/mol) 394.36
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