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Invitrogen™ ARTS Monoclonal Antibody (ARTS51)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA124693

Product Code. 11554762

  • 546.00 € / 50µL

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Description

Description

MA1-24693 is expected to cross react with mouse (100% conserved) due to sequence homology. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Apoptosis is related to many diseases and development. Mitochondrial proteins, such as cytochrome c, Apaf-1, and AIF play important role in apoptosis. A novel mitochondrial septin-like protein was identified recently and designated ARTS for apoptosis related protein in TGF-beta signaling pathway. ARTS that is encoded by the human septin H5/PNUTL2/CDCrel2b gene is located to mitochondria and translocates to the nucleus when apoptosis occurs. ARTS is expressed in many tissues. It enhances cell death induced by TGF-beta and, to a lesser extent, by other apoptotic agents, such as TNF-a and Fas ligand.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

ARTS
Monoclonal
2.2 mg/mL
PBS with 15mM sodium azide; pH 7.4
O43236
SEPTIN4
Synthetic peptide corresponding to C-terminal region (amino acids 247-266) of human ARTS protein, conjugated to KLH.
50 μL
Primary
Human
Antibody
IgG2b
ELISA, Immunoprecipitation, Western Blot, Immunocytochemistry
ARTS51
Unconjugated
SEPTIN4
4-Sep; apoptosis-related protein in the TGF-beta signaling pathway; ARTS; Bh5; BRADEION; Bradeion beta; brain protein H5; C17orf47; CE5B3; CE5B3 beta; cell division control-related protein 2; cell division control-related protein 2b; cerebral protein 7; EG3-1RVC; EG3RVC; expression gene 3 in rat visual cortex; expression gene 3-1 in rat visual cortex; H5; hCDCREL-2; hucep-7; MART; M-Septin; OTTMUSG00000001265; peanut-like 2; peanut-like 2 homolog; peanut-like protein 2; PNUTL2; SEP4; Sept4; septin 4; septin H5; Septin4; septin-4; septin-M; Uncharacterized protein C17orf47
Mouse
Purified
RUO
5414
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
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