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Description
This gene encodes a protein that contains an armadillo repeat and transmembrane domain. The encoded protein decreases the transcriptional activity of the tumor suppressor protein p53 through direct interaction with the DNA-binding domain of p53, and may play a role in cell growth and survival. Upregulation of this gene may play a role in hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 3.
Specifications
Specifications
| Antigen | ARMC10 |
| Applications | Western Blot, Immunohistochemistry (Paraffin), Immunoprecipitation |
| Classification | Polyclonal |
| Concentration | 0.2 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | ARMC10 |
| Gene Accession No. | B1WBW4, Q8N2F6, Q9D0L7 |
| Gene Alias | armadillo repeat containing 10, ARMC10, PNAS 112, SVH |
| Gene Symbols | Armc10 |
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