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Tocris Bioscience™ API-2

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:
10mg
Beskrivelse
API-2 is a selective inhibitor of Akt (protein kinase B) signaling; displays minimal inhibition of PKC, PKA, SGK and p38 pathways. Inhibits phosphorylation and activation of downstream targets of Akt including Bad, GSK-3β and AFX. Induces apoptosis and growth arrest in vitro, preferentially in human cancer cells with elevated levels of Akt. Potently and selectively inhibits growth of Akt-overexpressing tumors in mice. Inhibits DNA synthesis and displays antiviral activity against HIV-1 and -2.
Tekniske data
Tekniske data
| CAS | 35943-35-2 |
| Quantity | 10 mg |
| Molecular Formula | 1,5-Dihydro-5-methyl-1-β-D-ribofuranosyl-1,4,5,6,8-pentaazaacenaphthylen-3-amine |
| Product Type | API-2 |
| Purity | 99% |
| Molecular Weight (g/mol) | M.W. (Observed): 320.31 |
| Inhibitors | API-2 |
For Research Use Only
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