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ubiquitin protein ligase E3 component n-recognin 1, Mouse, Polyclonal Antibody, Abnova™
Description
The N-end rule pathway is one proteolytic pathway of the ubiquitin system. The recognition component of this pathway, encoded by this gene, binds to a destabilizing N-terminal residue of a substrate protein and participates in the formation of a substrate-linked multiubiquitin chain. This leads to the eventual degradation of the substrate protein. The protein described in this record has a RING-type zinc finger and a UBR-type zinc finger. Mutations in this gene have been associated with Johanson-Blizzard syndrome. [provided by RefSeq
Specifications
Specifications
| Antigen | ubiquitin protein ligase E3 component n-recognin 1 |
| Applications | ELISA, Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Mouse polyclonal antibody raised against a partial recombinant UBR1. |
| Formulation | 50% glycerol |
| Gene | UBR1 |
| Gene Accession No. | NM_17491 |
| Gene Alias | JBS/MGC142065/MGC142067 |
| Gene Symbols | UBR1 |
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