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transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) (B01), Mouse anti-Human, Polyclonal Antibody, Abnova™
Description
This gene encodes the protein elongin A, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. [provided by RefSeq
Specifications
Specifications
| Antigen | transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) |
| Applications | Immunofluorescence, Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Description | Mouse polyclonal antibody raised against a full-length human TCEB3 protein. |
| Formulation | No additive |
| Gene | TCEB3 |
| Gene Accession No. | NM_003198.1 |
| Gene Alias | FLJ38760/FLJ42849/SIII/TCEB3A |
| Gene Symbols | TCEB3 |
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