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GPR91, Polyclonal, Invitrogen™

Product Code. 13227898
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Quantity:
100 μg
Unit Size:
100µg
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13227898 100 μg 100µg
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Product Code. 13227898 Supplier Invitrogen Supplier No. PA523299

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Description

Rabbit Polyclonal Antibody

SUCNR1 is a 330 amino acid containing membrane receptor, belonging to the G-protein coupled receptor 1 family, characterized by an extracellular N terminus, seven transmembrane regions, and an intracellular C terminus and playing a role in cell communication. SUCNR1 a receptor for the citric acid cycle intermediate succinate, functions in establishing a neovascular network during development and in response to injury. SUCNR1, in response to increased succinate levels, regulates the production of numerous angiogenic factors including VEGF and may be involved in the modulation of platelet function. It is known to play an essential role in proliferative ischemic retinopathy and is an attractive target for treating diseases such as diabetic retinopathy that stem from aberrant neovascularization in the mature retina. Expression of SUCNR1 is common in kidney and in some other tissues.

TRUSTED_SUSTAINABILITY

Specifications

Antigen SUCNR1/GPR91
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5mg/mL
Conjugate Unconjugated
Gene SUCNR1
Gene Accession No. Q9BXA5
Gene Alias GPR91, G protein-coupled receptor 91, G-protein coupled receptor 91, P2Y purinoceptor 1
Gene Symbols SUCNR1
Host Species Rabbit
Immunogen Synthetic peptide (121 KYPFREHLLQKKE 133) of SUCNR1/GPR91 protein.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Primary or Secondary Primary
Gene ID (Entrez) 56670
Target Species Human, Non-human Primate
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Purified
Isotype IgG
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