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pyruvate dehydrogenase (lipoamide) alpha 1, Mouse, Purified MaxPab™ Polyclonal Antibody, Abnova™

Mouse polyclonal antibody raised against a full-length human PDHA1 protein.

Brand:  Abnova H00005160-B01P.50ug

Product Code. 16128861

  • 349.00 € / 50µg

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Description

Description

The pyruvate dehydrogenase complex is a nuclear-encoded mitochondrial matrix multienzyme complex that provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle by catalyzing the irreversible conversion of pyruvate into acetyl-CoA. The PDH complex is composed of multiple copies of 3 enzymes: E1 (PDHA1); dihydrolipoyl transacetylase (DLAT; MIM 608770) (E2; EC 2.3.1.12); and dihydrolipoyl dehydrogenase (DLD; MIM 238331) (E3; EC 1.8.1.4). The E1 enzyme is a heterotetramer of 2 alpha and 2 beta subunits. The E1-alpha subunit contains the E1 active site and plays a key role in the function of the PDH complex (Brown et al., 1994 [PubMed 7853374]).[supplied by OMIM

Sequence: MRKMLAAVSRVLSGASQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPPLEELGYHIYSSDPPFEVRGANQWIKFKSVS
Specifications

Specifications

pyruvate dehydrogenase (lipoamide) alpha 1
Polyclonal
Mouse polyclonal antibody raised against a full-length human PDHA1 protein.
PDHA1
PDHA/PDHCE1A/PHE1A
Mouse
Affinity Purified
RUO
5160
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
IgG
Immunohistochemistry (PFA fixed), Western Blot
Unconjugated
PBS with no preservative; pH 7.4
BC002406
PDHA1
PDHA1 (AAH02406, 1 a.a. ∼ 390 a.a) full-length human protein.
50 μg
Primary
Human, Mouse, Rat
Antibody
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