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pyruvate dehydrogenase (lipoamide) alpha 1, Mouse, Purified MaxPab™ Polyclonal Antibody, Abnova™
Mouse polyclonal antibody raised against a full-length human PDHA1 protein.
Brand: Abnova H00005160-B01P.50ug
Description
The pyruvate dehydrogenase complex is a nuclear-encoded mitochondrial matrix multienzyme complex that provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle by catalyzing the irreversible conversion of pyruvate into acetyl-CoA. The PDH complex is composed of multiple copies of 3 enzymes: E1 (PDHA1); dihydrolipoyl transacetylase (DLAT; MIM 608770) (E2; EC 2.3.1.12); and dihydrolipoyl dehydrogenase (DLD; MIM 238331) (E3; EC 1.8.1.4). The E1 enzyme is a heterotetramer of 2 alpha and 2 beta subunits. The E1-alpha subunit contains the E1 active site and plays a key role in the function of the PDH complex (Brown et al., 1994 [PubMed 7853374]).[supplied by OMIM
Sequence: MRKMLAAVSRVLSGASQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPPLEELGYHIYSSDPPFEVRGANQWIKFKSVSSpecifications
| pyruvate dehydrogenase (lipoamide) alpha 1 | |
| Polyclonal | |
| Mouse polyclonal antibody raised against a full-length human PDHA1 protein. | |
| PDHA1 | |
| PDHA/PDHCE1A/PHE1A | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| 5160 | |
| Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. | |
| IgG |
| Immunohistochemistry (PFA fixed), Western Blot | |
| Unconjugated | |
| PBS with no preservative; pH 7.4 | |
| BC002406 | |
| PDHA1 | |
| PDHA1 (AAH02406, 1 a.a. ∼ 390 a.a) full-length human protein. | |
| 50 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody |
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