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Phospho-Histone H2A.X (Ser139), Polyclonal, Invitrogen™

Product Code. 10273470
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Quantity:
100 μL
Unit Size:
100µL
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10273470 100 μL 100µL
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Product Code. 10273470 Supplier Invitrogen Supplier No. LFPA0025

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Description

Rabbit Polyclonal Antibody

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2A family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif.

A suggested positive control for this product is HeLa cells treated with camptothecin.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-Histone H2A.X (Ser139)
Applications Western Blot
Classification Polyclonal
Concentration 0.5mg/mL
Conjugate Unconjugated
Gene H2AFX
Gene Accession No. P16104
Gene Alias H2A/X, H2AX, H2AX histone, histone H2AX
Gene Symbols H2AFX
Host Species Rabbit
Immunogen Synthetic peptide
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3014
Target Species Human
Content And Storage Store at -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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